High-density lipoprotein cholesterol raising

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Therapies for raising high-density lipoprotein cholesterol.

A low high-density lipoprotein cholesterol (HDL-C) level is one of the strongest predictors of coronary risk (1). The negative correlation between coronary artery disease (CAD) and plasma HDL-C has been attributed to the ability of HDL to take up cellular cholesterol from the periphery and to mediate the transport of excess cholesterol to the liver (reverse cholesterol transport, RCT) (2). In J...

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High -density lipoprotein cholesterol as a predictor for diabetes mellitus

Background: Diabetes is a prevalent chronic disease around the world. To evaluate risk of diabetes comprehensively, we developed a score model for the risk prediction with HDL-C as a protective factor. Methods: We extracted physical examination data of 2728 individuals. The data contain 18 demographic and clinical variables. To identify the statistical significant feature variables, the backwa...

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cholesterol/high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, non–high-density lipoprotein cholesterol, or low-density lipoprotein particle concentration and guideline categories of low-density lipoprotein cholesterol or non–high-density lipoprotein cholesterol

International clinical practice guidelines on dyslipidemia emphasize the importance of matching the use and intensity of statin therapy with the absolute risk of atherosclerotic cardiovascular disease (CVD). Indeed, independent of the baseline level of dyslipidemia, patients who have entered the intervention arms of randomized clinical trials of statin therapy with similar absolute risks of CVD...

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High-density lipoprotein metabolism and reverse cholesterol transport: strategies for raising HDL cholesterol

A key to effective treatment of cardiovascular disease is to understand the body's complex lipoprotein transport system. Reverse cholesterol transport (RCT) is the process of cholesterol movement from the extrahepatic tissues back to the liver. Lipoproteins containing apoA-I [highdensity lipoprotein (HDL)] are key mediators in RCT, whereas non-high-density lipoproteins (non-HDL, lipoproteins co...

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Does Raising High-Density Lipoprotein Matter?

The well-documented capacity of alcohol consumption to increase levels of high-density lipoprotein (HDL) cholesterol1 has generated attempts to assess the extent to which this effect might contribute to the reduced incidence of coronary heart disease (CHD) that has been observed in moderate consumers of alcohol.2 Several reports based on multiple regression models in observational cohort studie...

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ژورنال

عنوان ژورنال: Current Opinion in Cardiology

سال: 2013

ISSN: 0268-4705

DOI: 10.1097/hco.0b013e328362210d